I was doing some serious research online (hehe) and I came across the following two killer science quotes,

First you guess. Don’t laugh, this is the most important step. Then you compute the consequences. Compare the consequences to experience. If it disagrees with experience, the guess is wrong. In that simple statement is the key to science. It doesn’t matter how beautiful your guess is or how smart you are or what your name is. If it disagrees with experience, it’s wrong. That’s all there is to it.

– Richard Feynman, from a PBS show on Dr. Feynman. He was describing to his class how to look for a new law of physics

The great tragedy of science – the slaying of a beautiful hypothesis by an ugly fact.

– T H Huxley (1887-1975)

There are more great science quotes here.